Chicken Bubble Biscuit Bake Casserole – Easy Creamy Comfort Food Dinner

Introduction

Chicken Bubble Biscuit Bake Casserole is one of the easiest and most comforting dinners you can make with minimal effort and maximum flavor. This classic casserole combines tender shredded chicken, fluffy biscuit pieces, creamy sauce, and melted cheese into one hearty, satisfying dish that the whole family will love.

The “bubble” in this recipe comes from refrigerated biscuit dough that puffs up while baking, creating soft, pillowy pockets throughout the casserole. As it cooks, the biscuits soak up the rich, savory sauce and become incredibly flavorful. Every bite delivers creamy, cheesy goodness with perfectly cooked chicken and tender biscuits.

This recipe is especially popular because it uses simple pantry ingredients and comes together quickly. It’s perfect for busy weeknights, potlucks, meal prep, and feeding hungry crowds. Whether you’re new to cooking or an experienced home cook, this casserole is practically foolproof.

If you’re looking for a cozy, family-friendly meal that feels homemade and comforting, Chicken Bubble Biscuit Bake Casserole is guaranteed to become a favorite in your kitchen.

Ingredients

3 cups cooked chicken, shredded or cubed

2 cans (16 oz each) refrigerated biscuit dough, cut into quarters

1 can (10.5 oz) cream of chicken soup

1 cup sour cream

1 cup whole milk

1 ½ cups shredded cheddar cheese

½ cup shredded mozzarella cheese

1 teaspoon garlic powder

1 teaspoon onion powder

½ teaspoon black pepper

½ teaspoon salt (adjust to taste)

1 teaspoon dried parsley or Italian seasoning

Optional add-ins: frozen peas, corn, broccoli

Preparation
Step 1:

Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish with butter or cooking spray.

Step 2:

Cut the biscuit dough into quarters and place the pieces in a large mixing bowl.

Step 3:

Add shredded chicken, cream of chicken soup, sour cream, milk, garlic powder, onion powder, salt, black pepper, and dried parsley to the bowl. Mix gently until everything is well combined.

Step 4:

Fold in cheddar and mozzarella cheese, making sure the biscuits and chicken are evenly coated with the creamy mixture.

Step 5:

Transfer the mixture into the prepared baking dish and spread evenly. Bake uncovered for 40–45 minutes, until biscuits are cooked through and the top is golden and bubbly.

Variations

Bacon Ranch Version: Add cooked bacon and ranch seasoning

Spicy Style: Mix in diced jalapeños or cayenne pepper

Veggie Loaded: Add carrots, spinach, or green beans

Buffalo Chicken: Stir in buffalo sauce and blue cheese

Low-Fat Option: Use light sour cream and reduced-fat cheese

Cooking Note

Because biscuits expand while baking, avoid packing the casserole too tightly. Spread evenly so heat circulates and cooks the dough completely.

Serving Suggestions

Serve with a fresh green salad

Pair with steamed vegetables

Add coleslaw on the side

Serve with fruit salad for balance

Enjoy with iced tea or lemonade

Tips

Use rotisserie chicken to save time

Cut biscuits evenly for uniform cooking

Cover loosely with foil if top browns too fast

Let casserole rest 5 minutes before serving

Check center biscuits to ensure doneness

Prep Time:

15 minutes

Cooking Time:

40–45 minutes

Total Time:

55–60 minutes

Nutritional Information (per serving, approximate)

Calories: 560

Protein: 34g

Sodium: 880mg

FAQs

Can I make this casserole ahead of time?
Yes. Assemble it, cover, and refrigerate up to 24 hours before baking.

Can I freeze Chicken Bubble Biscuit Bake?
It’s best fresh, but you can freeze after baking. Reheat in the oven for best texture.

Why are my biscuits doughy in the middle?
This happens if the casserole is too crowded. Spread evenly and bake fully.

Can I use homemade biscuits?
Yes, but refrigerated dough works best for consistent results.

What cheese works best?
Cheddar, mozzarella, Colby Jack, or a blend all work well.

Conclusion

Chicken Bubble Biscuit Bake Casserole is the ultimate comfort food—creamy, cheesy, fluffy, and incredibly satisfying. With tender chicken, soft biscuit pieces, and rich sauce baked together in one dish, this recipe delivers everything you want in a family-friendly meal. Easy to prepare and impossible to resist, it’s perfect for weeknights, gatherings, and anytime you crave homemade comfort.

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